The action of psilocybin and psilocin is similar to the action of LSD, according to some psychiatrists, these substances cause a psychomimetic syndrome similar to the manifestations of schizophrenia. The first symptoms appear 15-20 minutes after the use of psilocybe, when taken on a full stomach – after about 2 hours. Initially, there are dazedness, tremor, euphoria, delirium, anxiety, paranoia, an increase in auditory and visual susceptibility, a feeling of distortion of space and time, a violation of the perception of speed, light, and color, then unusual visions, hallucinations appear, the sensation of space and time disappears, a person seems to watch his own body from the side. As is the case with many other psychedelic substances, the effects and sensations after purchasing magic mushrooms online and taking it can vary greatly from person to person and from setting to setting.
Emotional experiences during the trip can be both positive and negative, and their type depends on many factors: if you feel unwell, or overworked, you may experience increased sensitivity to psilocybin and the emergence of negative emotions. With the development of a negative type of psilocybin syndrome, there is a feeling of anxiety, fits of rage, aggressiveness, a tendency to violence, including in relation to oneself, delirium, and complete loss of consciousness is possible. There may be recurring panic attacks, sometimes suicide attempts. With a positive type of psychedelic experience, there is a feeling of happiness, laughter, liberation from feelings of oppression, erotic attraction, depersonalization, and color hallucinations, during which there is a feeling of moving in space and time. An important role is played by the mental balance of a person and the general level of culture, the circumstances in which a person is taking hallucinogenic mushrooms.
The manifestations of the syndrome
Psilocybin syndrome is accompanied by an increase in the activity of the sympathetic nervous system, as a result of which pupil dilation, an increase in heart rate, an increase in body temperature are observed, proprioceptive sensitivity changes, and motor, and speech coordination is disturbed. A person experiencing a trip is fully aware of the unreality of what is happening.
Physical dependence and withdrawal symptoms do not develop with the use of psilocybin, but with regular use, mental dependence can occur. Animal experiments have shown that high doses of “magic” mushrooms can lead to demyelination (destruction of myelin sheaths) and dystrophic changes in hippocampal neurons. Some psilocybes, in particular P.semilanceata, can lead to heart problems and kidney failure. Psilocybin mushrooms are the least dangerous drug used for recreational purposes, according to the results of the study of the negative effects of drugs. Other researchers also note psilocybin’s “striking non-toxicity” to organs in the human body, emphasizing that the risks associated with taking psilocybin mushrooms are indirect: large doses can cause feelings of fear, which can lead to risky behavior.